"Professor Song Jae-whan’s Research Team Succeeds in Controlling FAD"
Protein Controlling Cancer Cell FAKiller Discovered
Prof. Song Jae-whan (Biochemistry) of MKRN1 in cancer cells increases and his research team succeeded effectiveness of treatments for cancer by in controlling FADD, an adaptor augmenting FADD adaptor protein levels. protein that is involved in preventing Prof. Song said that, “The research is growth of cancer cells. the first of its kind to reveal the principle FADD adaptor protein induces behind the degradation of FADD adaptor destruction of cancer cells, but the
protein. groundbreaking improvements principle behind its control was in anticancer treatment are expected unknown. The research team found
when a drug hindering MKRN1 activity that FADD can be regulated by Makorin is developed and taken along with other Ring Finger Protein 1 (MKRN1) E3 treatments.” ligase-mediated ubiquitination and The research results were published proteasomal degradation. It was proven in Nature Communication, the online that down regulation of MKRN1 results sister journal of the leading science in severe defects of tumour growth journal Nature.