The research on chromosome-centric human proteome, led by the Yonsei Proteome Research Center, has been designated in the Top 5 outstanding scientific research by the 2012 Korean Bio Research News. The research team’s article entitled “Uniting ENCODE with genome-wide proteomics” (corresponding authors Professor Paik Young-ki and WCU Professor William S. Hancock WCU Professor) was published in Nature Biotechnology (IF 23.2) on November 10th. The team’s study proposed a new approach to the chromosome-centric human proteome project with examples from Chromosomes 13 and 17. The study presents a global protein decoding map which makes out the basic structure, function, and location within cells and decodes the structural transformation information related to diseases that have such proteins.